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EDMONTON – Homeowners are now allowed to take down two tonnes of snow from their roofs and use it for snowblower parts as early as the end of this week.
Canada’s major banks have approved some kind of snow removal plan for at least 90 days for properties where access to electricity has been shut down.
Bank of Montreal (BMO) says the plan submitted for the 90-day duration has been approved.
READ MORE: Banks okayed bill to force homeowners to clear snow from driveways: CBC
The plan, which starts on January 15, will allow homeowners to use their downspouts and snowplows to clear their property. They can only move the snow
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.TRPC3
Canonical transient receptor potential channel 3 is a protein encoded by the TRPC3 gene in humans.
The protein encoded by this gene belongs to the transient receptor potential family of cation channels. The protein may form homodimers or heterodimers with other members of the TRPC family. It was previously named TRPC1, and named TRPC3 in the Human Gene Nomenclature Committee (HGNC) database.
The TRP family of genes encodes a large group of proteins that are putative nonselective cation channels or membrane receptors. These proteins have common structural features including six transmembrane domains, the TRP domain, and intracellular N and C termini. TRP proteins are also known as Transient Receptor Potential channels or cation channels. The TRP family is divided into seven subfamilies (TRPC, TRPV, TRPM, TRPP, TRPML, TRPA, and TRPML). The TRPC subfamily is named for the founding member of the family, TRPC1, which was originally called the Connexin-like protein 26 (CPLX1). The seven members of this subfamily are grouped into three clusters based on their predicted topology and the presence of N and C termini.
This gene encodes a TRPC3 protein containing seven transmembrane domains.
Function
TRPC3 protein is involved in intracellular Ca2+ signaling via its interaction with phospholipase C and the subsequent activation of calmodulin-dependent protein kinase II. The overexpression of TRPC3 in SH-SY5Y cells causes upregulation of c-fos and c-jun as well as the expression of c-myc.
TRPC3 has been implicated in prostaglandin generation. Aromatase regulates prostaglandin generation through TRPC3 and TRPC1 protein.
Knockout studies in the mouse have shown that TRPC3 is important for embryonic and fetal development. Homozygous mice die during late gestation. Additionally, male homozygous animals are infertile. Female animals have slightly reduced fertility because of increased apoptosis at mid-gestation.
Mutants of this protein have been associated with behavioral disorders in mice.
TRPC3 is implicated